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Now in its Sixth Edition, Clinical Epidemiology: The Essentials is a comprehensive, concise, and clinically oriented introduction to the subject of epidemiology. Written by expert educators, this approachable, informative text introduces students to the principles of evidence-based medicine that will help them develop and apply methods of clinical observation in order to form accurate conclusions. The updated sixth edition reflects the most current approaches to clinical epidemiology, including the latest coverage of modeling and expanded insight on applying concepts to clinical practice, with updated, clinical vignette-style end-of-chapter questions to help strengthen students' understanding and ensure a confident transition to clinical settings.